Gene:  UGT1A1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a UDP-glucuronosyltransferase an enzyme of the glucuronidation pathway that transforms small lipophilic molecules such as steroids bilirubin hormones and drugs into water-soluble excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin although it also has moderate activity with simple phenols flavones and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: UGT1A1, Human
UDP glucuronosyltransferase 1 family, polypeptide A1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0048773
Info:   Same primer pair as used in probe assay qHsaCEP0056033
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: UGT1A1, Human
UDP glucuronosyltransferase 1 family, polypeptide A1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014210
Info:   Recommended - best efficiency
List Price:    $174.00
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PrimePCR™ Probe Assay: UGT1A1, Human
UDP glucuronosyltransferase 1 family, polypeptide A1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0056033
List Price:    $255.00
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